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Acute Knockdown of Uncoupling Protein-2 Increases Uncoupling via the Adenine Nucleotide Transporter and Decreases Oxidative Stress in Diabetic Kidneys

Increased O(2) metabolism resulting in chronic hypoxia is common in models of endstage renal disease. Mitochondrial uncoupling increases O(2) consumption but the ensuing reduction in mitochondrial membrane potential may limit excessive oxidative stress. The present study addressed the hypothesis tha...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Friederich-Persson, Malou, Aslam, Shakil, Nordquist, Lina, Welch, William J., Wilcox, Christopher S., Palm, Fredrik
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2012
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388100/
https://ncbi.nlm.nih.gov/pubmed/22768304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039635
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