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NFAT5 Is Activated by Hypoxia: Role in Ischemia and Reperfusion in the Rat Kidney

The current hypothesis postulates that NFAT5 activation in the kidney's inner medulla is due to hypertonicity, resulting in cell protection. Additionally, the renal medulla is hypoxic (10–18 mmHg); however there is no information about the effect of hypoxia on NFAT5. Using in vivo and in vitro...

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Détails bibliographiques
Auteurs principaux: Villanueva, Sandra, Suazo, Cristian, Santapau, Daniela, Pérez, Francisco, Quiroz, Mariana, Carreño, Juan E., Illanes, Sebastián, Lavandero, Sergio, Michea, Luis, Irarrazabal, Carlos E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388090/
https://ncbi.nlm.nih.gov/pubmed/22768306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039665
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