Triadin/Junctin Double Null Mouse Reveals a Differential Role for Triadin and Junctin in Anchoring CASQ to the jSR and Regulating Ca(2+) Homeostasis

Triadin (Tdn) and Junctin (Jct) are structurally related transmembrane proteins thought to be key mediators of structural and functional interactions between calsequestrin (CASQ) and ryanodine receptor (RyRs) at the junctional sarcoplasmic reticulum (jSR). However, the specific contribution of each...

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Autors principals: Boncompagni, Simona, Thomas, Monique, Lopez, Jose R., Allen, Paul D., Yuan, Qunying, Kranias, Evangelia G., Franzini-Armstrong, Clara, Perez, Claudio F.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388061/
https://ncbi.nlm.nih.gov/pubmed/22768324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039962
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