Triadin/Junctin Double Null Mouse Reveals a Differential Role for Triadin and Junctin in Anchoring CASQ to the jSR and Regulating Ca(2+) Homeostasis

Triadin (Tdn) and Junctin (Jct) are structurally related transmembrane proteins thought to be key mediators of structural and functional interactions between calsequestrin (CASQ) and ryanodine receptor (RyRs) at the junctional sarcoplasmic reticulum (jSR). However, the specific contribution of each...

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Main Authors: Boncompagni, Simona, Thomas, Monique, Lopez, Jose R., Allen, Paul D., Yuan, Qunying, Kranias, Evangelia G., Franzini-Armstrong, Clara, Perez, Claudio F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388061/
https://ncbi.nlm.nih.gov/pubmed/22768324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039962
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