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Fidaxomicin Is an Inhibitor of the Initiation of Bacterial RNA Synthesis
Fidaxomicin was recently approved for the treatment of Clostridium difficile infection. It inhibits transcription by bacterial RNA polymerase. Because transcription is a multistep process, experiments were conducted in which fidaxomicin was added at different stages of transcriptional initiation to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3388026/ https://ncbi.nlm.nih.gov/pubmed/22752861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cis358 |
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