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Generation of Thiocillin Ring Size Variants by Prepeptide Gene Replacement and In Vivo Processing by Bacillus cereus

The thiocillins from Bacillus cereus ATCC 14579 are natural products from the broader class of thiazolyl peptides. Their biosynthesis proceeds via extensive post-translational modification of a ribosomally encoded precursor peptide. This post-translational tailoring involves a key step formal cycloa...

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Detalhes bibliográficos
Main Authors: Bowers, Albert A., Acker, Michael G., Young, Travis S., Walsh, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387813/
https://ncbi.nlm.nih.gov/pubmed/22686940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302820x
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