Can ends justify the means?: Telomeres and the mechanisms of replicative senescence and immortalization in mammalian cells
Finite replicative lifespan, or senescence, of mammalian cells in culture is a phenomenon that has generated much curiosity since its description. The obvious significance of senescence to organismal aging and the development of cancer has engendered a long-lasting and lively debate about its mechan...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1998
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33878/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9078 |
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