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Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation

In mammalian neurons, targeting and translation of specific mRNAs in dendrites contribute to synaptic plasticity. After nuclear export, mRNAs designated for dendritic transport are generally assumed to be translationally dormant and activity of individual synapses may locally trigger their extrasoma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chua, John Jia En, Schob, Claudia, Rehbein, Monika, Gkogkas, Christos G., Richter, Dietmar, Kindler, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387777/
https://ncbi.nlm.nih.gov/pubmed/22761992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00484
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