A mutation in the 530 loop of Escherichia coli 16S ribosomal RNA causes resistance to streptomycin.
Oligonucleotide-directed mutagenesis was used to introduce an A to C transversion at position 523 in the 16S ribosomal RNA gene of Escherichia coli rrnB operon cloned in plasmid pKK3535. E. coli cells transformed with the mutated plasmid were resistant to streptomycin. The mutated ribosomes isolated...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
1988
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| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338768/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3054810/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.20.9631 |
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