High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer

For patients with metastatic breast cancer, we previously described that increased EZH2 expression levels were associated with an adverse outcome to tamoxifen therapy. Main objective of the present study is to investigate miR-26a and miR-101 levels, which both target EZH2, for their association with...

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Autori principali: Jansen, M. P. H. M., Reijm, E. A., Sieuwerts, A. M., Ruigrok-Ritstier, K., Look, M. P., Rodríguez-González, F. G., Heine, A. A. J., Martens, J. W., Sleijfer, S., Foekens, J. A., Berns, E. M. J. J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2011
Soggetti:
Preclinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387494/
https://ncbi.nlm.nih.gov/pubmed/22094936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1877-4
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