Programmed Death-1(+) T Cells and Regulatory T Cells Are Enriched in Tumor-Involved Lymph Nodes and Associated with Aggressive Features in Papillary Thyroid Cancer

CONTEXT: Recurrent metastatic lymph node (LN) disease is common in patients with papillary thyroid cancer (PTC). Novel prognostic markers may be helpful in guiding a therapeutic approach. Our previous studies revealed that immune suppression is evident in PTC and associated with more severe disease....

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Hlavní autoři: French, Jena D., Kotnis, Gregory R., Said, Sherif, Raeburn, Christopher D., McIntyre, Robert C., Klopper, Joshua P., Haugen, Bryan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2012
Témata:
Hot Topics in Translational Endocrinology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387418/
https://ncbi.nlm.nih.gov/pubmed/22466343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-3428
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