Molecular mimicry between cockroach and helminth glutathione S-transferases promotes crossreactivity and cross-sensitization

BACKGROUND: The extensive similarities between helminth proteins and allergens are thought to contribute to helminth-driven allergic sensitization. OBJECTIVE: To investigate the cross-reactivity between a major glutathione-S transferase (GST) allergen of cockroach (Bla g 5) and the GST of Wuchereria...

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Autores principales: Santiago, Helton, LeeVan, Elyse, Bennuru, Sasisekhar, Ribeiro-Gomes, Flavia, Mueller, Ellen, Wilson, Mark, Wynn, Thomas, Garboczi, David, Urban, Joseph, Mitre, Edward, Nutman, Thomas B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387355/
https://ncbi.nlm.nih.gov/pubmed/22541242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.02.045
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