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Mitoxantrone Induces Natural Killer Cell Maturation in Patients with Secondary Progressive Multiple Sclerosis

Mitoxantrone is one of the few drugs approved for the treatment of progressive multiple sclerosis (MS). However, the prolonged use of this potent immunosuppressive agent is limited by the appearance of severe side effects. Apart from its general cytotoxic effect, the mode of action of mitoxantrone o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chanvillard, Coralie, Millward, Jason M., Lozano, Marta, Hamann, Isabell, Paul, Friedemann, Zipp, Frauke, Dörr, Jan, Infante-Duarte, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387260/
https://ncbi.nlm.nih.gov/pubmed/22768101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039625
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