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mTOR Is Essential for the Proteotoxic Stress Response, HSF1 Activation and Heat Shock Protein Synthesis

The target of rapamycin (TOR) is a high molecular weight protein kinase that regulates many processes in cells in response to mitogens and variations in nutrient availability. Here we have shown that mTOR in human tissue culture cells plays a key role in responses to proteotoxic stress and that redu...

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Bibliografski detalji
Glavni autori: Chou, Shiuh-Dih, Prince, Thomas, Gong, Jianlin, Calderwood, Stuart K.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387249/
https://ncbi.nlm.nih.gov/pubmed/22768106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039679
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