Neuroprotection of Tanshinone IIA against Cerebral Ischemia/Reperfusion Injury through Inhibition of Macrophage Migration Inhibitory Factor in Rats

BACKGROUND: Ischemia/reperfusion (I/R) injury is associated with systemic inflammatory response. Macrophage migration inhibitory factor (MIF) has been implicated in many inflammatory processes. Tanshinone IIA (TSA) is one of the active ingredients in danshen, which derived from the dried root or rhi...

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Bibliographic Details
Main Authors: Chen, Yanlin, Wu, Xuemei, Yu, Shanshan, Lin, Xuemei, Wu, Jingxian, Li, Lan, Zhao, Jing, Zhao, Yong
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387137/
https://ncbi.nlm.nih.gov/pubmed/22768247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040165
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