A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells

Cerebral malaria is the most deadly manifestation of infection with Plasmodium falciparum. The pathology of cerebral malaria is characterized by the accumulation of infected erythrocytes (IEs) in the microvasculature of the brain caused by parasite adhesins on the surface of IEs binding to human rec...

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Main Authors: Claessens, Antoine, Adams, Yvonne, Ghumra, Ashfaq, Lindergard, Gabriella, Buchan, Caitlin C., Andisi, Cheryl, Bull, Peter C., Mok, Sachel, Gupta, Archna P., Wang, Christian W., Turner, Louise, Arman, Mònica, Raza, Ahmed, Bozdech, Zbynek, Rowe, J. Alexandra
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387129/
https://ncbi.nlm.nih.gov/pubmed/22619330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120461109
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