An IFN-γ–stimulated ATF6–C/EBP-β–signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy

The IFN family of cytokines operates a frontline defense against pathogens and neoplastic cells in vivo by controlling the expression of several genes. The death-associated protein kinase 1 (DAPK1), an IFN-γ–induced enzyme, controls cell cycle, apoptosis, autophagy, and tumor metastasis, and its exp...

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Bibliographische Detailangaben
Hauptverfasser: Gade, Padmaja, Ramachandran, Girish, Maachani, Uday B., Rizzo, Mark A., Okada, Tetsuya, Prywes, Ron, Cross, Alan S., Mori, Kazutoshi, Kalvakolanu, Dhananjaya V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3387052/
https://ncbi.nlm.nih.gov/pubmed/22699507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119273109
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