Cryptopleurine Targets NF-κB Pathway, Leading to Inhibition of Gene Products Associated with Cell Survival, Proliferation, Invasion, and Angiogenesis

BACKGROUND: Cryptopleurine, a phenanthroquinolizidine alkaloid, was known to exhibit anticancer activity; however, the underlying mechanism is poorly understood. Because the nuclear factor-κB (NF-κB) transcription factors control many physiological processes including inflammation, immunity, and dev...

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Hlavní autoři: Jin, Hong Ri, Jin, Song Zhu, Cai, Xing Fu, Li, Donghao, Wu, Xue, Nan, Ji Xing, Lee, Jung Joon, Jin, Xuejun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386984/
https://ncbi.nlm.nih.gov/pubmed/22768286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040355
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