Cross-Talk between NFkB and the PI3-Kinase/AKT Pathway Can Be Targeted in Primary Effusion Lymphoma (PEL) Cell Lines for Efficient Apoptosis

BACKGROUND: A number of constitutively activated signaling pathways play critical roles in the survival and growth of primary effusion lymphoma cells (PELs) including NFkB and PI3/AKT kinase cascades. NFkBis constitutively activated in a number of malignancies, including multiple myeloma, Burkitt’s...

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Detalhes bibliográficos
Main Authors: Hussain, Azhar R., Ahmed, Saeeda O., Ahmed, Maqbool, Khan, Omar S., Al AbdulMohsen, Sally, Platanias, Leonidas C., Al-Kuraya, Khawla S., Uddin, Shahab
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386924/
https://ncbi.nlm.nih.gov/pubmed/22768179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039945
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