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ATP Release from Dying Autophagic Cells and Their Phagocytosis Are Crucial for Inflammasome Activation in Macrophages

Pathogen-activated and damage-associated molecular patterns activate the inflammasome in macrophages. We report that mouse macrophages release IL-1β while co-incubated with pro-B (Ba/F3) cells dying, as a result of IL-3 withdrawal, by apoptosis with autophagy, but not when they are co-incubated with...

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Detalhes bibliográficos
Main Authors: Ayna, Gizem, Krysko, Dmitri V., Kaczmarek, Agnieszka, Petrovski, Goran, Vandenabeele, Peter, Fésüs, László
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386917/
https://ncbi.nlm.nih.gov/pubmed/22768222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040069
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