A Retinoblastoma Orthologue Is a Major Regulator of S-Phase, Mitotic, and Developmental Gene Expression in Dictyostelium

BACKGROUND: The retinoblastoma tumour suppressor, Rb, has two major functions. First, it represses genes whose products are required for S-phase entry and progression thus stabilizing cells in G1. Second, Rb interacts with factors that induce cell-cycle exit and terminal differentiation. Dictyosteli...

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Bibliographic Details
Main Authors: Strasser, Kimchi, Bloomfield, Gareth, MacWilliams, Asa, Ceccarelli, Adriano, MacWilliams, Harry, Tsang, Adrian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386910/
https://ncbi.nlm.nih.gov/pubmed/22768168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039914
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