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Predicting protein-protein interface residues using local surface structural similarity

BACKGROUND: Identification of the residues in protein-protein interaction sites has a significant impact in problems such as drug discovery. Motivated by the observation that the set of interface residues of a protein tend to be conserved even among remote structural homologs, we introduce PrISE, a...

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Detalhes bibliográficos
Main Authors: Jordan, Rafael A, EL-Manzalawy, Yasser, Dobbs, Drena, Honavar, Vasant
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386866/
https://ncbi.nlm.nih.gov/pubmed/22424103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-41
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