Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors

The elastic modulus of bioengineered materials has a strong influence on the phenotype of many cells including cardiomyocytes. On polyacrylamide (PAA) gels that are laminated with ligands for integrins, cardiac myocytes develop well organized sarcomeres only when cultured on substrates with elastic...

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Main Authors: Chopra, Anant, Lin, Victor, McCollough, Amanda, Atzet, Sarah, Prestwich, Glenn D., Wechsler, Andrew S., Murray, Maria E., Oake, Shaina A., Kresh, J. Yasha, Janmey, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386849/
https://ncbi.nlm.nih.gov/pubmed/22196970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2011.11.023
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