Potential of ceragenin CSA-13 and its mixture with pluronic F-127 as treatment of topical bacterial infections

AIMS: Ceragenin CSA-13 is a synthetic mimic of cationic antibacterial peptides, with facial amphiphilic morphology reproduced using a cholic acid scaffold. Previous data have shown that this molecule displays broad-spectrum antibacterial activity, which decreases in the presence of blood plasma. How...

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Main Authors: Leszczyńka, K., Namiot, A., Cruz, K., Byfield, F. J., Won, E., Mendez, G., Sokolowski, W., Savage, P. B., Bucki, R., Janmey, P. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386848/
https://ncbi.nlm.nih.gov/pubmed/20961363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2672.2010.04874.x
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