FOXO1 in the ventromedial hypothalamus regulates energy balance

The transcription factor FOXO1 plays a central role in metabolic homeostasis by regulating leptin and insulin activity in many cell types, including neurons. However, the neurons mediating these effects and the identity of the molecular targets through which FOXO1 regulates metabolism remain to be d...

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Главные авторы: Kim, Ki Woo, Donato, Jose, Berglund, Eric D., Choi, Yun-Hee, Kohno, Daisuke, Elias, Carol F., DePinho, Ronald A., Elmquist, Joel K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386826/
https://ncbi.nlm.nih.gov/pubmed/22653058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62848
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