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CCAAT/Enhancer-Binding Proteins (C/EBP)-α and -β Are Essential for Ovulation, Luteinization, and the Expression of Key Target Genes

LH activation of the epidermal growth factor receptor/RAS/ERK½ pathway is essential for ovulation and luteinization because granulosa cell (GC) depletion of Erk½ (Erk½(gc)(−/−) mice) renders mice infertile. As mediators of ERK½-dependent GC differentiation, the CCAAT/enhancer-binding proteins, (C/EB...

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Autors principals: Fan, Heng-Yu, Liu, Zhilin, Johnson, Peter F., Richards, JoAnne S.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386543/
https://ncbi.nlm.nih.gov/pubmed/21177758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0318
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