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Recombinant fragment assay for gene targetting based on the polymerase chain reaction.
The modification of chromosomal genes by homologous recombination between exogenous DNA and a target locus provides a powerful approach to the study of gene function. One of the current limitations of this gene targetting is the difficulty of identifying cells containing the correctly modified targe...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1988
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC338641/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3174435/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.18.8887 |
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