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Patterns of Evolutionary Conservation of Essential Genes Correlate with Their Compensability

Essential genes code for fundamental cellular functions required for the viability of an organism. For this reason, essential genes are often highly conserved across organisms. However, this is not always the case: orthologues of genes that are essential in one organism are sometimes not essential i...

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Bibliografiske detaljer
Main Authors: Bergmiller, Tobias, Ackermann, Martin, Silander, Olin K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386227/
https://ncbi.nlm.nih.gov/pubmed/22761596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002803
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