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A role for myosin IXb, a motor–RhoGAP chimera, in epithelial wound healing and tight junction regulation

Polymorphisms in the gene encoding the heavy chain of myosin IXb (Myo9b) have been linked to several forms of inflammatory bowel disease (IBD). Given that Myo9b contains a RhoGTPase-activating protein domain within its tail, it may play key roles in Rho-mediated actin cytoskeletal modifications crit...

詳細記述

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書誌詳細
主要な著者: Chandhoke, Surjit K., Mooseker, Mark S.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386211/
https://ncbi.nlm.nih.gov/pubmed/22573889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-09-0803
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