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Molecular basis of Tank-binding kinase 1 activation by transautophosphorylation
Tank-binding kinase (TBK)1 plays a central role in innate immunity: it serves as an integrator of multiple signals induced by receptor-mediated pathogen detection and as a modulator of IFN levels. Efforts to better understand the biology of this key immunological factor have intensified recently as...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386122/ https://ncbi.nlm.nih.gov/pubmed/22619329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121552109 |
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