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Reactive oxygen species are second messengers of neurokinin signaling in peripheral sensory neurons

Substance P (SP) is a prominent neuromodulator, which is produced and released by peripheral damage-sensing (nociceptive) neurons; these neurons also express SP receptors. However, the mechanisms of peripheral SP signaling are poorly understood. We report a signaling pathway of SP in nociceptive neu...

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Detalhes bibliográficos
Main Authors: Linley, John E., Ooi, Lezanne, Pettinger, Louisa, Kirton, Hannah, Boyle, John P., Peers, Chris, Gamper, Nikita
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386117/
https://ncbi.nlm.nih.gov/pubmed/22586118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201544109
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