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Statistical properties of interval mapping methods on quantitative trait loci location: impact on QTL/eQTL analyses

BACKGROUND: Quantitative trait loci (QTL) detection on a huge amount of phenotypes, like eQTL detection on transcriptomic data, can be dramatically impaired by the statistical properties of interval mapping methods. One of these major outcomes is the high number of QTL detected at marker locations....

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Main Authors: Wang, Xiaoqiang, Gilbert, Hélène, Moreno, Carole, Filangi, Olivier, Elsen, Jean-Michel, Le Roy, Pascale
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386024/
https://ncbi.nlm.nih.gov/pubmed/22520935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-13-29
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