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Statistical properties of interval mapping methods on quantitative trait loci location: impact on QTL/eQTL analyses

BACKGROUND: Quantitative trait loci (QTL) detection on a huge amount of phenotypes, like eQTL detection on transcriptomic data, can be dramatically impaired by the statistical properties of interval mapping methods. One of these major outcomes is the high number of QTL detected at marker locations....

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Autori principali: Wang, Xiaoqiang, Gilbert, Hélène, Moreno, Carole, Filangi, Olivier, Elsen, Jean-Michel, Le Roy, Pascale
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386024/
https://ncbi.nlm.nih.gov/pubmed/22520935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-13-29
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