Statistical properties of interval mapping methods on quantitative trait loci location: impact on QTL/eQTL analyses

BACKGROUND: Quantitative trait loci (QTL) detection on a huge amount of phenotypes, like eQTL detection on transcriptomic data, can be dramatically impaired by the statistical properties of interval mapping methods. One of these major outcomes is the high number of QTL detected at marker locations....

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Bibliografiske detaljer
Main Authors: Wang, Xiaoqiang, Gilbert, Hélène, Moreno, Carole, Filangi, Olivier, Elsen, Jean-Michel, Le Roy, Pascale
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386024/
https://ncbi.nlm.nih.gov/pubmed/22520935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-13-29
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