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Transforming growth factor-β enhances invasion and metastasis in Ras-transfected human malignant epidermal keratinocytes

Transforming growth factor-β (TGF-β) is known to act as a tumour suppressor early in carcinogenesis, but then switches to a pro-metastatic factor in some late stage cancers. However, the actions of TGF-β are context dependent, and it is currently unclear how TGF-β influences the progression of human...

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Hlavní autoři: Davies, Maria, Prime, Stephen S, Eveson, John W, Price, Nicky, Ganapathy, Anu, D’Mello, Anita, Paterson, Ian C
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385707/
https://ncbi.nlm.nih.gov/pubmed/22414291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2011.00806.x
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