Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?

The c-Abl tyrosine kinase is implicated in diverse cellular activities including growth factor signaling, cell adhesion, oxidative stress, and DNA damage response. Studies in mouse models have shown that the kinases of the c-Abl family play a role in the development of the central nervous system. Re...

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Autores principales: Gonfloni, Stefania, Maiani, Emiliano, Di Bartolomeo, Claudia, Diederich, Marc, Cesareni, Gianni
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385657/
https://ncbi.nlm.nih.gov/pubmed/22761618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/683097
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