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Intercellular transfer regulation of the paracrine activity of GPI-anchored Cripto-1 as a Nodal co-receptor

Cripto-1 (CR-1) is a glycosylphosphatidylinositol-anchored glycoprotein which acts as an obligate co-receptor of a TGFβ family ligand, Nodal. Previous studies have demonstrated that CR-1 functions in a paracrine fashion by a cellular mechanism which has not been fully described. This paracrine activ...

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Bibliographic Details
Main Authors: Watanabe, Kazuhide, Salomon, David S.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385653/
https://ncbi.nlm.nih.gov/pubmed/21055389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.10.128
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