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GABA(B)-ergic motor cortex dysfunction in SSADH deficiency
OBJECTIVE: Succinic semialdehyde dehydrogenase (SSADH) deficiency is a rare autosomal recessive disorder of GABA degradation leading to elevations in brain GABA and γ-hydroxybutyric acid (GHB). The effect of chronically elevated GABA and GHB on cortical excitability is unknown. We hypothesized that...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Lippincott Williams & Wilkins
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3385496/ https://ncbi.nlm.nih.gov/pubmed/22722631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e31825dcf71 |
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