In Crohn's Disease, Anti-TNF-α Treatment Changes the Balance between Mucosal IL-17, FOXP3, and CD4 Cells

Aim. In Crohn's disease (CD), anti-TNF-α treatment is a potent medication. We aimed to characterize the effect of anti-TNF-α treatment on T effector and regulatory cells. Material and Methods. We studied T-effector and regulatory cells on cellular and mRNA levels in intestinal biopsy samples fr...

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Main Authors: Hölttä, Veera, Sipponen, Taina, Westerholm-Ormio, Mia, Salo, Harri M., Kolho, Kaija-Leena, Färkkilä, Martti, Savilahti, Erkki, Vaarala, Outi, Klemetti, Paula
Formato: Artigo
Idioma:Inglês
Publicado: International Scholarly Research Network 2012
Assuntos:
Clinical Study
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384926/
https://ncbi.nlm.nih.gov/pubmed/22778976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/505432
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