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KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas.

DNAs from human pancreatic adenocarcinomas were analyzed for the presence of mutations in codons 12, 13 and 61 of the NRAS, KRAS and HRAS gene. Formalin-fixed and paraffin-embedded tissue was used directly in an in vitro amplification reaction to expand the relevant RAS sequences. The mutations were...

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Bibliografski detalji
Glavni autori: Smit, V T, Boot, A J, Smits, A M, Fleuren, G J, Cornelisse, C J, Bos, J L
Format: Artigo
Jezik:Inglês
Izdano: 1988
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC338489/
https://ncbi.nlm.nih.gov/pubmed/3047672
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