CD4(+) T cell-mediated neuroprotection is independent of T cell-derived BDNF in a mouse facial nerve axotomy model

BACKGROUND: The production of neurotrophic factors, such as BDNF, has generally been considered an important mechanism of immune-mediated neuroprotection. However, the ability of T cells to produce BDNF remains controversial. METHODS: In the present study, we examined mRNA and protein of BDNF using...

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Hlavní autoři: Xin, Junping, Mesnard, Nichole A., Beahrs, Taylor, Wainwright, Derek A., Serpe, Craig J., Alexander, Thomas D., Sanders, Virginia M., Jones, Kathryn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384748/
https://ncbi.nlm.nih.gov/pubmed/22426430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.02.011
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