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Notch Signaling Is Necessary to Maintain Quiescence in Adult Muscle Stem Cells

Satellite cells (SCs) are myogenic stem cells found in skeletal muscle that function to repair tissue damaged by injury or disease. SCs are quiescent at rest, although the signaling pathways required to maintain quiescence are unknown. Using a transgenic Notch reporter mouse and quantitative reverse...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BJORNSON, CHRISTOPHER R.R., CHEUNG, TOM H., LIU, LING, TRIPATHI, PINKY V., STEEPER, KATHERINE M., RANDO, THOMAS A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384696/
https://ncbi.nlm.nih.gov/pubmed/22045613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.773
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