Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets

Osteopontin (Opn) is important for T helper type 1 (T(H)1) immunity and autoimmunity. However, the role of this cytokine in T(H)2-mediated allergic disease as well as its effects on primary versus secondary antigenic encounters remain unclear. Here we demonstrate that OPN is expressed in the lungs o...

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Hauptverfasser: Xanthou, Georgina, Alissafi, Themis, Semitekolou, Maria, Simoes, Davina C M, Economidou, Erasmia, Gaga, Mina, Lambrecht, Bart N, Lloyd, Clare M, Panoutsakopoulou, Vily
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384679/
https://ncbi.nlm.nih.gov/pubmed/17435770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1580
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