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Two Mechanisms Regulate Keratin K15 Expression In Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signalling

BACKGROUND: Keratin 15 (K15) is a type I keratin that is used as a marker of stem cells. Its expression is restricted to the basal layer of stratified epithelia, and the bulge in hair follicles. However, in certain clinical situations including oral lichen planus, K15 is induced in suprabasal layers...

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Detalhes bibliográficos
Main Authors: Bose, Amrita, Teh, Muy-Teck, Hutchison, Iain L., Wan, Hong, Leigh, Irene M., Waseem, Ahmad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384677/
https://ncbi.nlm.nih.gov/pubmed/22761689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038599
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