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Identification of Kinases Regulating Prostate Cancer Cell Growth Using an RNAi Phenotypic Screen

As prostate cancer progresses to castration-resistant disease, there is an increase in signal transduction activity. Most castration-resistant prostate tumors continue to express the androgen receptor (AR) as well as androgen-responsive genes, despite the near absence of circulating androgen in thes...

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Detalhes bibliográficos
Main Authors: Whitworth, Hilary, Bhadel, Shriti, Ivey, Melissa, Conaway, Mark, Spencer, Andrea, Hernan, Ronald, Holemon, Heather, Gioeli, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384611/
https://ncbi.nlm.nih.gov/pubmed/22761715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038950
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