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Inhibition of Chondrosarcoma Growth by mTOR Inhibitor in an In Vivo Syngeneic Rat Model

BACKGROUND: Chondrosarcomas are the second most frequent primary malignant type of bone tumor. No effective systemic treatment has been identified in advanced or adjuvant phases for chondrosarcoma. The aim of the present study was to determine the antitumor effects of doxorubicin and everolimus, an...

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Главные авторы: Perez, Jennifer, Decouvelaere, Anne Valérie, Pointecouteau, Thomas, Pissaloux, Daniel, Michot, Jean Philippe, Besse, Anthony, Blay, Jean Yves, Dutour, Aurélie
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384598/
https://ncbi.nlm.nih.gov/pubmed/22761648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032458
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