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Unveiling combinatorial regulation through the combination of ChIP information and in silico cis-regulatory module detection

Computationally retrieving biologically relevant cis-regulatory modules (CRMs) is not straightforward. Because of the large number of candidates and the imperfection of the screening methods, many spurious CRMs are detected that are as high scoring as the biologically true ones. Using ChIP-informati...

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Detalhes bibliográficos
Main Authors: Sun, Hong, Guns, Tias, Fierro, Ana Carolina, Thorrez, Lieven, Nijssen, Siegfried, Marchal, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384348/
https://ncbi.nlm.nih.gov/pubmed/22422841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks237
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