The role of N-terminus of Plasmodium falciparum ORC1 in telomeric localization and var gene silencing

Plasmodium falciparum origin recognition complex 1 (ORC1) protein has been implicated in DNA replication and silencing var gene family. However, the mechanism and the domain structure of ORC1 related to the regulation of var gene family are unknown. Here we show that the unique N-terminus of PfORC1...

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Bibliografski detalji
Glavni autori: Deshmukh, Abhijit S., Srivastava, Sandeep, Herrmann, Susann, Gupta, Ashish, Mitra, Pallabi, Gilberger, Tim Wolf, Dhar, Suman Kumar
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Gene Regulation, Chromatin and Epigenetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384324/
https://ncbi.nlm.nih.gov/pubmed/22379140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks202
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