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Engineering naturally occurring trans-acting non-coding RNAs to sense molecular signals

Non-coding RNAs (ncRNAs) are versatile regulators in cellular networks. While most trans-acting ncRNAs possess well-defined mechanisms that can regulate transcription or translation, they generally lack the ability to directly sense cellular signals. In this work, we describe a set of design princip...

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Hlavní autoři: Qi, Lei, Lucks, Julius B., Liu, Chang C., Mutalik, Vivek K., Arkin, Adam P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384300/
https://ncbi.nlm.nih.gov/pubmed/22383579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks168
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