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Distinct perturbation of the translatome by the antidiabetic drug metformin
Metformin has been reported to lower cancer incidence among type II diabetics. Metformin exhibits antiproliferative and antineoplastic effects associated with inhibition of mammalian target of rapamycin complex 1 (mTORC1), but the mechanisms are poorly understood. We provide a unique genome-wide ana...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3384216/ https://ncbi.nlm.nih.gov/pubmed/22611195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201689109 |
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