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Stress-induced epigenetic regulation of κ-opioid receptor gene involves transcription factor c-Myc

Exposure to stress is associated with adverse emotional and behavioral responses. Whereas the κ-opioid receptor (KOR) system is known to mediate some of the effects, it is unclear whether and how stress affects epigenetic regulation of this gene. Because the KOR gene can use two promoters (Pr1 and P...

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Bibliographische Detailangaben
Hauptverfasser: Flaisher-Grinberg, Shlomit, Persaud, Shawna D., Loh, Horace H., Wei, Li-Na
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3384167/
https://ncbi.nlm.nih.gov/pubmed/22615378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205565109
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